This guide contains information about places where you can stop for the night when driving from Portsmouth, New Hampshire to Myrtle Beach, South Carolina. Total distance for the trip is around 922 miles with a driving time of approximately 14 hours 21 mins. Cities and towns with hotels that are on the fastest route between Portsmouth and Myrtle Beach are listed below. (Driving times are approximate and will vary with traffic and weather conditions.)

56.8 miles from Portsmouth (1 hour 3 mins)
874 miles from Myrtle Beach (13 hours 38 mins)
150 miles from Portsmouth (2 hours 23 mins)
776 miles from Myrtle Beach (12 hours 6 mins)
186 miles from Portsmouth (2 hours 55 mins)
741 miles from Myrtle Beach (11 hours 37 mins)
264 miles from Portsmouth (4 hours 27 mins)
661 miles from Myrtle Beach (10 hours 14 mins)
273 miles from Portsmouth (4 hours 31 mins)
653 miles from Myrtle Beach (10 hours 3 mins)
356 miles from Portsmouth (5 hours 50 mins)
572 miles from Myrtle Beach (8 hours 54 mins)
384 miles from Portsmouth (6 hours 9 mins)
545 miles from Myrtle Beach (8 hours 25 mins)
393 miles from Portsmouth (6 hours 18 mins)
532 miles from Myrtle Beach (8 hours 14 mins)
449 miles from Portsmouth (7 hours 12 mins)
475 miles from Myrtle Beach (7 hours 20 mins)
487 miles from Portsmouth (7 hours 54 mins)
435 miles from Myrtle Beach (6 hours 39 mins)
546 miles from Portsmouth (8 hours 46 mins)
384 miles from Myrtle Beach (5 hours 47 mins)
601 miles from Portsmouth (9 hours 32 mins)
327 miles from Myrtle Beach (4 hours 54 mins)
624 miles from Portsmouth (9 hours 52 mins)
305 miles from Myrtle Beach (4 hours 33 mins)
684 miles from Portsmouth (10 hours 46 mins)
247 miles from Myrtle Beach (3 hours 49 mins)
726 miles from Portsmouth (11 hours 19 mins)
211 miles from Myrtle Beach (3 hours 21 mins)
810 miles from Portsmouth (12 hours 29 mins)
120 miles from Myrtle Beach (2 hours 3 mins)

Popular Hotels In Myrtle Beach

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Please make sure you read your reservation's cancellation policy!
You'll be given this information with the available room rates after you select a hotel and specify dates. Many hotels have cancellation penalties associated with their best rates. Most offer "Book Now and Pay Later" options that are less restrictive, but slightly more expensive.